(A.G.E) Advanced Glycation Endproducts-

Our body grows old for several internal and external reasons.
Among them: genetic predisposition, changes in the hormonal background, photoaging due to exposure to sunlight, nutritional deficiencies, the effects of toxins (tobacco, alcohol, etc.).
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📌In the center of the mechanism of aging there are two chemical reactions - oxidation and glycation.
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✅Glikation is a chemical reaction that occurs as a result of fixation of free sugars on protein molecules. It affects the entire body. At the last stage of this chemical reaction, the final products of glycosylation appear - Advanced Glycation Endproducts (A.G.E). They are one of the main causes of skin aging, because the effects of glycation are most susceptible to elastin and collagen, the proteins of the dermis. Over time, they become increasingly stiff and harder because of the increasing fixation of sugars on protein molecules. And as a result: flabbiness, wrinkles, pigmentation and redness, a violation of skin scarring. All these signs of aging are directly or indirectly caused by the process of glycosylation, which in our body occurs continuously, and with age only worsens.
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✅ Among the common effects of glycation, the most important are: weakening of immunity, renal failure, damage to nerve cells (Alzheimer's disease), complications of diabetes, clouding of the eye crystal, cardiovascular problems.
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✅ In dermatology, the results of glycation are manifested in increased vascular permeability and their expansion, deterioration of the properties of elastin and collagen, slowing the healing process of scars and wounds.
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At birth, the level of glycation in the body of a young child is very low, but with age it is getting higher and higher - the process of accumulation of the final products of glycosylation - A.G.E. For example, the higher the level of glycation in the body, the faster and stronger a person will have bruises after minor strokes and heal the wounds longer. It is the level of glycation that corresponds to our biological age.
Unfortunately, our body does not have a protective system against glycation.